Two respected scientists (Matthew Goode and Toni Collette) quit their jobs at a prestigious university and tackle their biggest experiment to date — parenthood! Raising three children against their genetic predispositions, they seek to prove that everyone has the same potential to become anything they choose.

The big question being, are we born as we are, or can we blame our parents for who we become? Hilarity ensues as this unconventional family soon discovers the ultimate power of nurture over nature.